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A small tree, Steganotaenia araliacae is used as a medicine in local traditional settings in Zambia to initiate and augment parturition although very little is known and documented about its physiological and pharmacological effects. S. araliacae extract (SAEᶜ) has been observed to cause...

The cerebellar tonsils are part of the nervous system which is the chief controlling and coordinating system of the body. Their functional role is not yet known but are believed to coordinate skilled and learned movements. The cerebellar tonsils are prone to herniation through the foramen magnum...

Background Many HIV-infected patients are accessing antiretroviral therapy (ART) in Zambia. This has enabled them to live longer. However, it is necessary to determine whether such improvements are accompanied with parallel improvements in quality of life. The purpose of this research was to...

There has been some evidence that because of life saving combination Antiretroviral therapy (cART), people living with HIV are living longer and it is apparent that they are at an increased risk of developing non communicable diseases (NCD) including diabetes mellitus. Despite this recognition,...

Zinc, Copper and Selenium are important trace elements in human health and disease. They play a vital role as cofactors of enzymes such as superoxide dismutase and glutathione peroxide. These act as first line antioxidants enzymes in red blood cells and in plasma. In sickle-cell anaemia patients,...

Acute lymphoblastic leukaemia is a malignant disease that evolves as a result of mutation of lymphoid precursor cells. The World Health Organization recognizes that the genetic analysis of leukaemia has prognostic and therapeutic implications. Cytogenetic and molecular studies provide important...

Spontaneous abortion in Zambia is defined as non-induced embryonic death or passage of products of conception before 28 weeks’ gestation. Placental insufficiency as a result of thrombi lodging in the uteroplacental bed is considered to be a cause of pregnancy loss. Circulating microparticles are...

The study was conducted to determine whether there was a difference in clinical decision making between nurses and midwives trained in Emergency Obstetric and Neonatal Care (EmONC) and the untrained on referral of obstetric emergencies and whether there was a relationship between being trained in...

John Cunningham virus (JC virus) is a polyomavirus that causes Progressive Multifocal Leukoencephalopathy (PML) a debilitating and often fatal disease of the central nervous system. JC virus is ubiquitous, approximately 50% of adults globally have antibodies against the virus and about 30%...

Human African Trypanosomiasis (HAT) causes severe economic production losses in humans due to loss of man power and death. In Zambia most of the studies that have been done have focused on analysing the parasite while none have been conducted to establish the economic consequences of the burden...