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Zinc, Copper and Selenium are important trace elements in human health and disease. They play a vital role as cofactors of enzymes such as superoxide dismutase and glutathione peroxide. These act as first line antioxidants enzymes in red blood cells and in plasma. In sickle-cell anaemia patients,...

Introduction: Hepatic tumour is a joint term for a diverse group of liver tumours which are caused by a variety of agents and fall into primary or secondary hepatic tumours. A tumour is an abnormal benign or malignant new growth of tissue that may or may not possess physiological functions and...

Spontaneous abortion in Zambia is defined as non-induced embryonic death or passage of products of conception before 28 weeks’ gestation. Placental insufficiency as a result of thrombi lodging in the uteroplacental bed is considered to be a cause of pregnancy loss. Circulating microparticles are...

Vitamin B12 and folate deficiency is a well-known health problem. Deficiencies of folic acid and vitamin B12 are known to cause megaloblastic anaemia, which is characterised by presence of abnormally large erythrocyte precursor cells, megaloblasts, in the bone marrow and macrocytic red cells in...

Background Human papilloma virus (HPV) infection is the most common sexually transmitted infection that commonly affects both males and females, yet much of the information about it centres on women because it is associated with cervical cancer, the most common malignancy in women of child...

With the increasing availability of highly active antiretroviral therapy (HAART), people are living longer with human immunodeficiency virus (HIV) infection. Effective antiretroviral therapy (ART) for HIV has resulted in a great reduction of acquired immunodeficiency syndrome (AIDS)-related...

Context - A number of biomarkers are implicated in the pathophysiology of hypertension. Low adiponectin levels have been associated with hypertension and this might be due to its effects on endothelial nitric oxide synthase levels. Aims - In this study we aimed to assess plasma adiponectin and...

thrombogenic marker d-dimer are strongly associated with a higher mortality risk in patients with HIV infection. Aims – The aim of the study was to determine if D-Dimer levels in conjunction with IL 6 levels, as markers of predisposition to thrombosis, are higher in HIV positive than in HIV...

Context: Multiple myeloma (MM) is the second most common blood cancer after lymphomas, thereby accounting for 10% of all haematological malignancies. The incidence of MM is related to age with the condition being more common in the elderly. There is a higher incidence and mortality rate among...

Background: Patients with diabetes mellitus have a high risk of atherothrombotic events. Eighty percent of patients with diabetes mellitus die due to thrombosis, and 75% of these deaths are due to cardiovascular complications. A cross-sectional analytical study was conducted at Ndola Central...