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Introduction: Globally, bacterial infections are a major cause of morbidity and mortality, particularly in low income countries. The global emergence of antimicrobial resistance undermines the management of infectious diseases. Internationally, there is a growing concern over antimicrobial...

World Health Organization reports that about 1.24 million people die annually on the world’s roads, with 20–50 million sustaining non-fatal injuries. More than 85% (1.05 million) of the global deaths due to injuries occur in the developing world. Statistical techniques known and applied to model...

Pneumonia in sickle cell disease (SCD) can be particularly severe and has come to be called acute chest syndrome (ACS). ACS is a frequent complication of sickle cell disease in patients hospitalized with vaso-occlusive crisis (VOC). It is associated with a high risk of sickle cellrelated...

Malaria in pregnancy causes adverse birth outcomes. Intermittent preventive treatment of malaria during pregnancy with sulphadoxine-pyrimethamine (IPTp-SP) is recommended as a chemoprevention therapy. Despite the effectiveness of the intervention, Zomba district has below national average uptake...

There has been some evidence that because of life saving combination Antiretroviral therapy (cART), people living with HIV are living longer and it is apparent that they are at an increased risk of developing non communicable diseases (NCD) including diabetes mellitus. Despite this recognition,...

Tenofovir disoproxil fumerate (TDF)-based antiretroviral therapy places HIV-infected patients at high risk of renal dysfunction. Therefore, we evaluated if the incidence of renal dysfunction in HIV positive adults patients on long term tenofovir-based regimen versus those on non-tenofovir use. We...

Background: Toxoplasmosis is a neglected disease and in Africa its seroprevalence ranges from 18.7% - 92.5%. About 3% -10% HIV/AIDS - Toxoplasmosis co-infected patients die from the later. This study aimed to determine the seroprevalence and determinants of the disease among pregnant women...

BACKGROUND Globally about 34 million people are living with HIV/AIDS, and annually 2.5 million new infections and 1.7 million deaths related to AIDS occur. Zambia in particular is experiencing a generalized HIV/AIDS epidemic, with a national HIV prevalence rate of 14.3 percent among adults aged...

Taenia Solium cysticercosis is a zoonotic infection endemic in many developing countries. It occurs mainly in rural communities and is associated with poverty, poor sanitation and free-range pig management. Humans act as the definitive host (taeniasis) and pigs and humans as the intermediate...

Background:Of the estimated 130 million infants born each year worldwide, 4 million die in the first 28 days of life illustrating how neonatal mortality accounts for almost 40 percent of under-five child mortality, globally. The continued loss of infants within the first month of life results...