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Background Environmental enteropathy is prevalent in many low and middle-income countries. Although its aetiology is unknown, we hypothesised that nontuberculous mycobacteria (NTMs), which are ubiquitous in the environment and are known to cause disease in the lungs, the gut, skin, bloodstream...

Background: Cirrhosis is a dominant cause of portal hypertension globally but is overshadowed by schistosomiasis in parts of the tropics, including in Zambia where hepatosplenic schistosomiasis (HSS) sero-prevalence can reach 88% in some districts. Bacterial translocation (BT) drives portal...

Background: Oral vaccines have been associated with diminished immunogenicity and efficacy in developing country populations. Rotavirus, cholera and oral polio vaccines have shown much lower protection in Africa and Asia than in developed countries. In view of this, there is an urgent need to...

Introduction There is a shortage of systematically collected data on gastric cancer in Zambia. An audit carried out as preliminary work showed that there was a change in the epidemiology of gastric cancer since the early 1980s, and it was hypothesised that this change was linked to HIV infection....