Context— The transcriptional regulation of lipogenesis is a highly coordinated process that is controlled by insulin. Fatty acid synthase (FASN) plays a central role in de novo lipogenesis by converting acetyl-CoA and malonyl-CoA into the final end product, palmitate, which may subsequently be...
Download PDF ↓Background: Medication errors can occur at any of the five steps of the medication use process: prescribing, transcription, dispensing, administration and monitoring. AIM: This study aimed to ascertain the incidence and types of prescribing and administration errors. METHODS: The study was a...
Download PDF ↓INTRODUCTION: Tuberculosis is recognised as one the leading causes of severe sepsis among HIV positive patients. Most patients with tuberculosis mycobacteraemia have advanced HIV disease with CD4 counts less than 100cells/ul and many do not present with the classical signs of tuberculosis....
Download PDF ↓INTRODUCTION: Tuberculosis is recognised as one the leading causes of severe sepsis among HIV positive patients. Most patients with tuberculosis mycobacteraemia have advanced HIV disease with CD4 counts less than 100cells/ul and many do not present with the classical signs of tuberculosis....
Download PDF ↓INTRODUCTION: Tuberculosis is recognised as one the leading causes of severe sepsis among HIV positive patients. Most patients with tuberculosis mycobacteraemia have advanced HIV disease with CD4 counts less than 100cells/ul and many do not present with the classical signs of tuberculosis....
Download PDF ↓Background and aim: Carotid femoral pulse wave velocity (cfPWV) is considered as the gold standard for directly estimating central arterial stiffness. Furthermore, the simultaneous measurement of central blood pressure (CBP) with cfPWV is augmentative. This is because the two are strong and...
Primary mania is the diagnostic label given to manic episodes that occur during the course of a Bipolar Disorder (Ghanem KG, 2008). Patients with secondary mania have manic-like episodes somewhat similar to those seen in Bipolar Disorder. (Lyketsos CG et al, 1997). However, these manic-like...
Candida species have emerged as successful pathogens in both invasive and mucosal infections, especially in immunocompromised patients. Additionally, there is increasing resistance of Candida species to antifungal agents, and this has greatly contributed to the high morbidity and mortality...
Download PDF ↓Context: Multiple myeloma (MM) is the second most common blood cancer after lymphomas, thereby accounting for 10% of all haematological malignancies. The incidence of MM is related to age with the condition being more common in the elderly. There is a higher incidence and mortality rate among...
Download PDF ↓Introduction: Atrial fibrillation (AF) and congestive heart failure (CHF) have emerged as major global epidemics. These two conditions share common risk factors and frequently coexist. Each condition predisposes to the other, and the concomitant presence of the two has additive adverse effects....
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