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Acute lymphoblastic leukaemia is a malignant disease that evolves as a result of mutation of lymphoid precursor cells. The World Health Organization recognizes that the genetic analysis of leukaemia has prognostic and therapeutic implications. Cytogenetic and molecular studies provide important...

Spontaneous abortion in Zambia is defined as non-induced embryonic death or passage of products of conception before 28 weeks’ gestation. Placental insufficiency as a result of thrombi lodging in the uteroplacental bed is considered to be a cause of pregnancy loss. Circulating microparticles are...

The study was conducted to determine whether there was a difference in clinical decision making between nurses and midwives trained in Emergency Obstetric and Neonatal Care (EmONC) and the untrained on referral of obstetric emergencies and whether there was a relationship between being trained in...

Introduction: The spectrum of renal diseases in HIV infected adults undergoing biopsy is vast. Previous studies have indicated that HIV-associated nephropathy (HIVAN) is the commonest diagnosis in HIV-infected patients presenting with renal insufficiency. More than 90% of patients with HIVAN are...

Background: The Traditional goal of intensive care has been to reduce short-term mortality. While worthwhile in terms of “saving lives”, this goal fails to address the issue of what it means to survive intensive care (ICU). Key questions include whether ICU survivors have optimal long-term...

Background A birth certificate provides legal recognition of the identity of a child, and as such, birth registration in Zambia is compulsory. Data derived from birth registration is critical in health planning and research. Few births are registered despite being provided free of charge or at a...

Background: Globally, about 287,000 women die from causes related to pregnancy and childbirth and 162,000 of these are in Sub-Saharan Africa. 16 million adolescent women (aged 15–19) give birth every year around the world and about 95% of these births are concentrated in middle and low income...

John Cunningham virus (JC virus) is a polyomavirus that causes Progressive Multifocal Leukoencephalopathy (PML) a debilitating and often fatal disease of the central nervous system. JC virus is ubiquitous, approximately 50% of adults globally have antibodies against the virus and about 30%...

Background- Psychiatric co-morbidities, particularly mood and anxiety disorders, occur more frequently in patients with epilepsy compared to the general population and tend to worsen morbidity and mortality in this group of patients via suicide among other causes. Treatment of these disorders is...

Background: Congenital Rubella Syndrome (CRS) characterised by heart, eye and hearing defects usually affects an unborn baby when the mother is infected with Rubella virus in the first trimester of pregnancy. It is vaccine preventable and has been eliminated in certain parts of the world. In...