thrombogenic marker d-dimer are strongly associated with a higher mortality risk in patients with HIV infection. Aims – The aim of the study was to determine if D-Dimer levels in conjunction with IL 6 levels, as markers of predisposition to thrombosis, are higher in HIV positive than in HIV...
Download PDF ↓Background: The pathogenesis of human hypertension is complex and multifactorial. Haptoglobin genes have been cited as risk factors in the development of hypertension. Haptoglobin is an α2-glycoprotein acute phase reactant that binds to free haemoglobin and forms a stoichiometrically stable...
Download PDF ↓Context: Multiple myeloma (MM) is the second most common blood cancer after lymphomas, thereby accounting for 10% of all haematological malignancies. The incidence of MM is related to age with the condition being more common in the elderly. There is a higher incidence and mortality rate among...
Download PDF ↓Introduction:Breast cancer remains among the most commonly diagnosed cancers in women. Worldwide, breast cancer comprises 22.9% of all cancers. In Zambia, it is ranked number 2 at 11% after cervical cancer (60%). However, the current prevalence can be reduced through sensitization programmes...
Download PDF ↓Title: Serum levels of Lipoprotein(a) in HIV positive patients on HAART at Livingstone General Hospital, Livingstone, Southern Province, Zambia. Background: Lipoprotein(a) (Lp(a)) is a highly atherogenic independent risk marker for Cardiovascular disease (CVD) and current studies have shown that...
Download PDF ↓Background: Diabetic nephropathy (DN) is a kidney disease that is a complication of diabetes. Pathogenesis of DN involves damage to the tiniest blood vessels which is followed by increased concentration of blood urea / creatinine and urine albumin excretion. DN is the leading cause of morbidity...
Download PDF ↓Background: Patients with diabetes mellitus have a high risk of atherothrombotic events. Eighty percent of patients with diabetes mellitus die due to thrombosis, and 75% of these deaths are due to cardiovascular complications. A cross-sectional analytical study was conducted at Ndola Central...
Download PDF ↓Malaria is a disease of great public health importance in Zambia. It is a major cause of morbidity and mortality and is endemic in all nine provinces. The malaria transmission paradigms may be higher in urban populations than in peri-urban and rural population and peri-urban areas tend to become...
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