BACKGROUND:Glucose-6-phosphate dehydrogenase (G6PD) enzyme deficiency is the most common enzymopathy in humans and affects over 400 million people worldwide, majority being in Africa. G6PD catalyses the first reaction of the pentose phosphate pathway where it plays a role in generation of NADPH,...
Download PDF ↓Background and aim: Carotid femoral pulse wave velocity (cfPWV) is considered as the gold standard for directly estimating central arterial stiffness. Furthermore, the simultaneous measurement of central blood pressure (CBP) with cfPWV is augmentative. This is because the two are strong and...
Introduction: Atrial fibrillation (AF) and congestive heart failure (CHF) have emerged as major global epidemics. These two conditions share common risk factors and frequently coexist. Each condition predisposes to the other, and the concomitant presence of the two has additive adverse effects....
Download PDF ↓Background: Diabetes mellitus is one of the main growing public health concerns worldwide. There are two major types of diabetes mellitus. Type 1 diabetes mellitus which appears early in life and Type 2 diabetes mellitus which appears in adult life. It is important to regularly monitor the...
Download PDF ↓Studies have suggested that Sub-Sahara Africans are prone to HIV-related renal dysfunction. A study done in Zambia showed increased deaths among HIV/AIDS patients who had renal dysfunction. Tenofovir Disoproxil Fumarate (TDF) one of the first line antiretroviral drugs in Zambia, has been...
Download PDF ↓Background: The bark root of Steganotaenia araliacea Hochst (Umbelliferae) nicknamed “herbal pitocin” is used in the traditional circles in Zambia to induce and/or enhance labour. This work was aimed at investigating the contractile stimulatory effects of the aqueous extracts of Steganotaenia...
Download PDF ↓BACKGROUND: Hyponatremia, defined as serum sodium less than 135mmol/l, is a very common disorder in neonates. It accounts for about 30% of hospitalised cases worldwide, especially in premature neonates admitted to an intensive care unit. The overall morbidity and mortality from hyponatremia...
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