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Title: The correlation between baseline serum hepatitis B surface antigen level and levels of other baseline markers of viral activity in chronic hepatitis B viral infection at the University Teaching Hospital. Background: Hepatitis B viral (HBV) infection rate among healthy blood donors in...

Background:Amphotericin-B deoxycholate is an essential agent in the management of cryptococcal meningitis. Despite its proven antifungal potency it has several untoward side effects which include renal failure, hypomagnesaemia, hypokalaemia, phlebitis and nephrogenic diabetes insipidus....

Introduction: Pulmonary disease is a leading cause of morbidity and mortality in HIV-infected patients. Yet specific causes are often unknown in third-world settings due to a lack of extensive diagnostic facilities, particularly in patients with sputum smear negative for acid-alcohol fast bacilli...

BACKGROUND Sepsis accounts for a significant burden of morbidity and mortality. In developed countries, it has been implicated as the second leading cause of non-cardiac death. Mortality from sepsis is on the increase with mortality rate of 33-61%. In spite of the high burden of sepsis in...

To determine the prevalence of drug adherence and factors associated with poor adherence to antihypertensive treatment Objective:among adults seen in the department of medicine at UTH. To investigate patient related and health care system related factors associated with poor adherence to...

Infection with HIV ultimately results in profound immunodeficiency, in which patients may present with various AIDS – defining clinical conditions.The CD4+T-cell count is an important parameter to understand HIV-related opportunistic infections. In poor countries and populations with limited...

Introduction There is a shortage of systematically collected data on gastric cancer in Zambia. An audit carried out as preliminary work showed that there was a change in the epidemiology of gastric cancer since the early 1980s, and it was hypothesised that this change was linked to HIV infection....

Background Heart failure is a major public health problem and has been recognized as an important cause of morbidity and mortality for several years. It is one of the leading non-infectious causes of death among hospitalized patients at the University Teaching Hospital (UTH) in Lusaka, Zambia....

Introduction:Stroke is an important cause of morbidity and mortality at UTH. It is important to know the nature of stroke and the clinical outcome of different types of strokes in our setting.This study was designed to determine the frequency and types of strokes in patients admitted at UTH and...

Despite the highest disease burden of HIV, Sub-Saharan Africa has limited data on HIV related kidney disease in the region. Kidney disease is a recognised complication in HIV infected patients, presenting with either can be acute renal failure (ARF) or chronic kidney disease (CKD). This study...