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Oxidative stress has been associated with many diseases, causing injury on cells, tissues and organs. Due the complications associated with it, conventional medicines have used antioxidants like minerals and vitamins in its management. Several plants have been shown to be rich in substances that...

Zinc, Copper and Selenium are important trace elements in human health and disease. They play a vital role as cofactors of enzymes such as superoxide dismutase and glutathione peroxide. These act as first line antioxidants enzymes in red blood cells and in plasma. In sickle-cell anaemia patients,...

In low-and middle-income countries (LMICs) the maintenance of standards relating to the transport and storage of blood may be more difficult to achieve. Bacteria contamination and hyperkalemia represent two significant risks. The objectives of this study were to assess the viability of transfused...

Context— The transcriptional regulation of lipogenesis is a highly coordinated process that is controlled by insulin. Fatty acid synthase (FASN) plays a central role in de novo lipogenesis by converting acetyl-CoA and malonyl-CoA into the final end product, palmitate, which may subsequently be...

Background: Sickle Cell Disease (SCD) is highly prevalent in Africans. The SCD trait is 18% in the general population in Zambia and University Teaching Hospital in Lusaka has under its care over 1500 SCD patients. SCD causes high morbidity and mortality. Patients with SCD often have pathologies...

Objective: To determine the effect Kigelia africana fruit extract has on blood glucose levels of diabetes mice and its phytochemical profile Specific objectives: 1. To determine Kigelia africana fruit extracts’ effect on blood glucose levels when used alone and concomitantly with Glibenclamide on...

Background: HIV1&2, HBsAg, anti-HCV and syphilis antibody are mandatory disease marker tests of Transfusion Transmissible Infections (TTIs) conducted on every donated unit of blood in Zambia. Blood is donated by first time voluntary donors and repeat/regular donors of different ages. Both...

Perioperative Normovolaemic Haemodilution was done on twenty three patients who had major elective orthopaedic surgery both at the University Teaching Hospital, Lusaka and the Zambian - Italian Orthopaedic Hospital, Lusaka between July, 1997 and June, 1999. There were twelve males and eleven...

Perioperative Normovolaemic Haemodilution was done on twenty three patients who had major elective orthopaedic surgery both at the University Teaching Hospital, Lusaka and the Zambian - Italian Orthopaedic Hospital, Lusaka between July, 1997 and June, 1999.There were twelve males and eleven...

To determine the incidence, common indications,appropriateness and outcome of blood transfusions and blood products among adult in-patients admitted to the University teaching Hospital, Lusaka, Zambia. Prospective observational study over a period of 90 days.The university Teaching Hospital and...