Chronic MyeloidLeukaemia (CML) is consistently associated with a characteristic chromosome translocation called the Philadelphia (Ph) chromosome. This translocation fuses sequences of theBreakpoint Cluster Region(BCR) gene from band q11 on chromosome 22 with regions of theAbelson(ABL) gene from...
Download PDF ↓The major challenge of intensive care in Zambia is limited availability of resources. With the increase in the number of intensive care units in the country, a tool to evaluate and compare the standard of care across these units could be used to help direct resources and provide quality...
Download PDF ↓von Willebrand Disease (vWD) is the most common or prevalent inherited bleeding disorder. It is caused by a deficiency or dysfunction of von Willebrand Factor, which is a glycoprotein that carries Factor VIII (Anti haemophilic factor) and an adhesive protein in platelet-vessel wall interactions....
Download PDF ↓Background Tuberculosis (TB) remains a leading cause of mortality and morbidity worldwide, including Zambia, especially among the HIV infected. Both renal dysfunction and tuberculosis have been shown to be highly prevalent among hospitalised HIV infected patients. Little is known about how TB and...
Download PDF ↓Background Many HIV-infected patients are accessing antiretroviral therapy (ART) in Zambia. This has enabled them to live longer. However, it is necessary to determine whether such improvements are accompanied with parallel improvements in quality of life. The purpose of this research was to...
Download PDF ↓Introduction Delayed-healing in abdominal surgical wounds may be detrimental to patients and the health care. The author set out to investigate the effects of CD4+ count, serum albumin and haemoglobin (HB) levels on wound strength in HIV positive patients. Wound strength in this study is used to...
Download PDF ↓The thyroid gland is a butterfly-shaped endocrine organ located below and anterior to the larynx, at the base of the neck. It consists of two bulky lateral lobes connected by a thin isthmus. The thyroid gland produces, stores and releases hormones that control metabolism. These hormones include...
Download PDF ↓Background: The safe recovery of patients admitted to hospital depends on early detection of clinical and physiological deterioration and undertaking appropriate intervention to prevent mortality. Modified early warning score (MEWS) is a structured objective way of monitoring patients’ condition...
Download PDF ↓BACKGROUND Hydrotherapy plays an important role in the management of surgical patients, and especially so in those that have sustained burns to their skin. Different centers practice hydrotherapy differently. At the University Teaching Hospital in Lusaka, Zambia, patients with burns in surgical...
Download PDF ↓Background - New born deaths account for approximately 40% of all deaths under five years of age in developing countries with the three major causes being birth asphyxia, infections, and complications due to prematurity and low birth weight (LBW). Birth weight is a significant determinant of...
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