Background: The pathogenesis of human hypertension is complex and multifactorial. Haptoglobin genes have been cited as risk factors in the development of hypertension. Haptoglobin is an α2-glycoprotein acute phase reactant that binds to free haemoglobin and forms a stoichiometrically stable...
Download PDF ↓INTRODUCTION: Tuberculosis is recognised as one the leading causes of severe sepsis among HIV positive patients. Most patients with tuberculosis mycobacteraemia have advanced HIV disease with CD4 counts less than 100cells/ul and many do not present with the classical signs of tuberculosis....
Download PDF ↓Background and aim: Carotid femoral pulse wave velocity (cfPWV) is considered as the gold standard for directly estimating central arterial stiffness. Furthermore, the simultaneous measurement of central blood pressure (CBP) with cfPWV is augmentative. This is because the two are strong and...
Primary mania is the diagnostic label given to manic episodes that occur during the course of a Bipolar Disorder (Ghanem KG, 2008). Patients with secondary mania have manic-like episodes somewhat similar to those seen in Bipolar Disorder. (Lyketsos CG et al, 1997). However, these manic-like...
Candida species have emerged as successful pathogens in both invasive and mucosal infections, especially in immunocompromised patients. Additionally, there is increasing resistance of Candida species to antifungal agents, and this has greatly contributed to the high morbidity and mortality...
Download PDF ↓Context: Multiple myeloma (MM) is the second most common blood cancer after lymphomas, thereby accounting for 10% of all haematological malignancies. The incidence of MM is related to age with the condition being more common in the elderly. There is a higher incidence and mortality rate among...
Download PDF ↓Introduction: Atrial fibrillation (AF) and congestive heart failure (CHF) have emerged as major global epidemics. These two conditions share common risk factors and frequently coexist. Each condition predisposes to the other, and the concomitant presence of the two has additive adverse effects....
Download PDF ↓In its aim to meet the Millennium Development Goal (MDGs) number 6 on Malaria, Zambia through the National Malaria Control Centre (NMCC) has allocated nearly $200 million into prevention and control programs. These programs include the distribution of Insecticide Treated Nets (ITNs), Indoor...
Download PDF ↓Introdution: Under-five mortality, which is the probability of a child dying before their fifth birthday, is of concern in Zambia as infant and child mortality rates are important social indicators. Demographic health surveys conducted between 1992 and 2014 show notable reductions in under-five...
Download PDF ↓BACKGROUND: To help improve the foetal outcome, many professional bodies recommend the decision delivery interval (DDI) for emergency caesarean sections should be within 30 minutes. However, studies have not been conclusive to state whether delivering within 30 minutes would significantly improve...
Download PDF ↓