Context— The transcriptional regulation of lipogenesis is a highly coordinated process that is controlled by insulin. Fatty acid synthase (FASN) plays a central role in de novo lipogenesis by converting acetyl-CoA and malonyl-CoA into the final end product, palmitate, which may subsequently be...
Download PDF ↓Background: Sickle Cell Disease (SCD) is highly prevalent in Africans. The SCD trait is 18% in the general population in Zambia and University Teaching Hospital in Lusaka has under its care over 1500 SCD patients. SCD causes high morbidity and mortality. Patients with SCD often have pathologies...
Download PDF ↓Objective: To determine the effect Kigelia africana fruit extract has on blood glucose levels of diabetes mice and its phytochemical profile Specific objectives: 1. To determine Kigelia africana fruit extracts’ effect on blood glucose levels when used alone and concomitantly with Glibenclamide on...
Download PDF ↓Background: HIV1&2, HBsAg, anti-HCV and syphilis antibody are mandatory disease marker tests of Transfusion Transmissible Infections (TTIs) conducted on every donated unit of blood in Zambia. Blood is donated by first time voluntary donors and repeat/regular donors of different ages. Both...
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