Breast cancer (BC) patients in Zambia more commonly present with advanced-stage disease and often at young ages (≤50 years). Breast cancer gene 1 (BRCA1) is a tumor suppressor gene in which mutations have been linked to disease presentation at a young age. More than 600 distinct pathogenic...
Download PDF ↓Breast cancer is the second most common cancer in women in Zambia. It has been established that Oestrogen Receptor (ER), Progesterone Receptor (PR) and Human Epidermal Growth Factor Receptor 2 (HER2) are important markers for treatment and prognosis of breast cancer. Treatment has now become...
Download PDF ↓Breast Cancer gene 1 (BRCA1) and Breast Cancer gene 2 (BRCA2) have gained major scientific interest as potential prognostic and predictive markers for various tumours. Management of breast cancer depends on availability of robust clinical and pathological prognostic and predictive factors to...
Download PDF ↓The main objective of this study was to determine the prevalence of oestrogen receptor-negative breast cancers at UTH and CDH and its impact on tamoxifen management. The specific objectives of the study were to determine the prevalence of oestrogen receptor negative of breast cancer patients; to...
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