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Children co-infected with HIV-1 and malaria are more likely to suffer from malaria and may respond poorly to anti-malarial treatment due to immunosuppression resulting from HIV infection. This study provides results of antimalarial treatment outcomes in children co-infected with HIV and malaria....

Globally, there are 450,000 new cases and 234,000 deaths annually due to invasive cervical cancer (ICC). Eighty percent of these cases and deaths occur in the developing world.Sub-Saharan Africa bears a disproportionate burden due to ICC, with some of the highest incidence and mortality rates in...

Zambia is among countries in the Sub-Saharan African with high HIV seroprevalence Rates. In spite an increased awareness campaign concerning the dangers of HIV/AIDS and its prevention, the infection has continued to spread. The current impact of the HIV infection on childhood morbidity and...

Background Zambia is a resource constrained country with a Human Immunodeficiency Virus (HIV) prevalence of 16% among adults aged 15-49 years. The HIV sero prevalence in urban antenatal clinics is approximately 25% and it is estimated that 28,000 infants are born with HIV infection annually....

Treatment of HIV related diarrhoea has been a problem due to lack of effective chemotherapeutic agents against the different organisms responsible for the problem. Following the promising results of a double blind randomised placebo controlled study at the University Teaching Hospital, Lusaka ,...

Zambia similar to other sub Saharan countries has high sero prevalence rates of HIV. In spite of several campaigns and strategies to improve HIV/AIDS awareness, paediatric HIV/AIDS cases in Zambia continue to rise. Despite the now available ARV's, few children are brought forward to access care....

Background: In most developed countries HIV testing, use of antiretroviral drugs (ARVs) and modification of feeding practices have greatly reduced the rate of mother to child transmission (MTCT) of HIV-1 though this is not the case in many African countries. In Zambia, prevention of mother to...

In most developed countries HIV testing, use of antiretroviral drugs (ARVs) and modification of feeding practices have greatly reduced the rate of mother to child transmission (MTCT) of HIV-1 though this is not the case in many African countries. In Zambia, prevention of mother to child...

Reported here are factors that influence the morbidity and mortality in hospitalised Zambian children with measles. A prospective study on 2174 children was undertaken to analyse the clinical presentations and complications in children hospitalised for measles between 1993 to 1996 and between...

The introduction of antiretroviral therapy has transformed HIV care and lead to significant reduction in morbidity and mortality worldwide. In resource poor setting like Zambia, HIV-infected children often start treatment with advanced disease stage against a background of a high burden of...