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Zambian children under age 5 continue to face multiple obstacles with respect to their survival and development. Specifically, beyond the neonatal period, Pneumonia, and Diarrhoea are leading contributors to the high under-5 mortality rate. While vaccinations have been introduced to counter these...

The incidence of HIV-associated Kaposi’s sarcoma remains high in Zambia in the antiretroviral therapy era. The most efficacious treatment regimen for KS has yet to be established. In both developed and developing countries, treatment regimens have had limited efficacy. Late presentation in Africa...

Acute Respiratory Infection (ARI) is one of the leading causes of morbidity and mortality among children under the age of five years globally accounting for 16% of deaths. In Zambia, ARI accounts for 30-40% of children’s outpatient attendance and 20-30% of hospital admissions. The study therefore...

Plague is a re-emerging flea-borne infectious disease of global importance and in recent years Zambia has periodically experienced increased incidence of bubonic plague outbreaks. However, there are currently no studies in the country that provide a quantitative assessment of the ability of the...

Human Parvovirus (B19V) is a small, single-stranded, non-enveloped DNA virus which is pathogenic to humans causing a wide array of clinical complications which include erythema infectiosum, aplastic crisis and hydrops foetalis. It is generally harmless in healthy individuals but may be life...

Diabetes Mellitus (DM) is known to be associated with active tuberculosis (TB). Zambia remains a high TB burden country with reports of increasing DM amongst developing countries. However, to date, few relevant studies have originated from Zambia. The strength of the association remains...

Background: Chronic HIV infection is associated with renal complications including renal dysfunction. Risk factors found in literature for kidney disease in the HIV population include hypertension, diabetes mellitus, cardiovascular disease, low CD4 count, high viral load, hepatitis C virus...

An estimated 2 million people are being newly infected, and 1.2 million people are dying of Human Immune Virus (HIV) – related causes (WHO, 2015). Despite significant success in scaling up Anti-retroviral Therapy (ART) programmes worldwide, many people living with HIV (PLHIV) start ART late in...

Male latex condoms are 80–95 percent effective in preventing HIV and most STIs when used consistently and correctly. HIV/AIDS is the most dramatic epidemic of the century that has claimed more than 3 million deaths over two decades. Sub-Saharan Africa is heavily affected and accounts for nearly...

Background: Antiretroviral therapy has posed multiple risks and challenges particularly in resource constrained African countries. This is due to the chronic nature of HIV/AIDS disease and hence its therapy, the use of combination therapy and also because therapeutic options and treatment...