Most countries in sub-Saharan Africa are encouraged to adopt WHO recommended Option B+, but there is a general fear that the evidence for its effectiveness has not been demonstrated in different settings. Option B+ is an intervention that ensures administering of life-long HIV treatment to HIV...
Background HIV is a cross-cutting problem which does not only affect adults but also affects adolescents. The number of adolescents living with HIV is increasing due to the provision of Highly Active Antiretroviral Therapy (HAART) which enables them to live longer yet little is known about their...
Download PDF ↓Background This cross-sectional study described factors affecting access to antiretroviral therapy among HIV-positive children (0-15 years) out of the comprehensive HIV Care program using informal caregivers in Chipata district, Eastern Province of Zambia. Methods Data was collected between...
Download PDF ↓1.0 Abstract Introduction The effectiveness of anti-retroviral therapy (ART) relies on a strict adherence to it. To achieve optimum therapeutic levels and reduce drug resistance requires levels ≥95% adherence. As such, identifying factors to adherence is essential. We sought to determine factors...
Download PDF ↓Non-tuberculosis Mycobacteria (NTM) are increasingly recognized as human pathogens especially with the emergence of Acquired Immunodeficiency Syndrome (AIDS). Similarity of clinical symptoms with TB, coupled with limited diagnostic capacities in tuberculosis (TB)- endemic areas has led to...
Download PDF ↓Introduction: Pneumonia is a leading cause of morbidity and a significant cause of mortality worldwide. Although information is available on pneumonia in children in Zambia, the incidence in adults in many parts of Africa including Zambia is unknown. Knowledge of the local aetiological agents of...
Download PDF ↓Globally, opportunistic infections due to environmental Non-tuberculous Mycobacteria are increasingly becoming a public health threat due to the Human Immunodeficiency Virus and Acquired Immunodeficiency Syndrome pandemic. In Zambia, Non tuberculous Mycobacteria are gaining recognition as...
Download PDF ↓Background: Method: Results: Conclusion Sepsis due to respiratory disease is one of the main complications of HIV/AIDS. Audit data from the Department of Internal Medicine at the University Teaching Hospital in Lusaka, Zambia indicate that pneumonia and tuberculosis in HIV represent two of the...
Hepatitis B virus (HBV) survives and replicates in the liver. In adults, it is mostly transmitted sexually. Because of this shared route with Human Immune Deficiency Virus (HIV), it is highly prevalent in HBV infected patients In sub-Saharan Africa, the prevalence of HBV is between 6-20%. In...
Download PDF ↓Introduction: The burden of cardiovascular disease (CVD) in Sub-Saharan Africa is rising in the background of a high prevalence of infectious diseases including Human Immune Deficiency Virus (HIV). The use of certain Antiretroviral Therapy (ART) drugs has been shown to cause dyslipidaemia, with...