The study sought to investigate the presence of Micro-albuminuria (MA) in urine. MA urinary albumin excretion is in the range of 30 mg/24 hrs -300 mg/24 hrs. Consequently, urine albumin excretion has become a key therapeutic target in the management of patients with diabetes mellitus (DM). We...
Download PDF ↓Tenofovir disoproxil fumerate (TDF)-based antiretroviral therapy places HIV-infected patients at high risk of renal dysfunction. Therefore, we evaluated if the incidence of renal dysfunction in HIV positive adults patients on long term tenofovir-based regimen versus those on non-tenofovir use. We...
Download PDF ↓Introduction: The spectrum of renal diseases in HIV infected adults undergoing biopsy is vast. Previous studies have indicated that HIV-associated nephropathy (HIVAN) is the commonest diagnosis in HIV-infected patients presenting with renal insufficiency. More than 90% of patients with HIVAN are...
Background: Improved medical care has led to improved life expectancy of sickle cell anaemia (SCA) patients hence complications associated with SCA such as chronic kidney disease (CKD) are being seen more frequently. Globally, nephropathy of varying severity occurs in 5 to 18 % of the SCA...
Download PDF ↓Context— Acute kidney injury (AKI) and chronic kidney disease (CKD) represent one of the important health problems with high morbidity and mortality in Zambia. Recognition of AKI allows prompt injury specific intervention that may avert permanent renal damage and progression of CKD to End Stage...
Download PDF ↓Introduction: Rhabdomyolysis is a frequent occurrence among trauma patients, with studies reporting an incidence of as high as 85% (Heurta-Aladin et al. 2004). Other studies however reported an incidence of as low as 6.7 %( Lawrence 2004). The incidence of Acute Kidney Injury (AKI) most studies...
Download PDF ↓Background: Diabetic nephropathy (DN) is a kidney disease that is a complication of diabetes. Pathogenesis of DN involves damage to the tiniest blood vessels which is followed by increased concentration of blood urea / creatinine and urine albumin excretion. DN is the leading cause of morbidity...
Download PDF ↓The high frequency with which elevated creatinine levels and proteinuria occur indicate the importance of closely monitoring serum and urine chemistries in HIV-infected patients, especially those with risk factors for renal dysfunction. 1.To describe the prevalence of renal dysfunction in...
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