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Shakachite, Lisa
2022·Master of Science·University of Zambia

Breast cancer (BC) patients in Zambia more commonly present with advanced-stage disease and often at young ages (≤50 years). Breast cancer gene 1 (BRCA1) is a tumor suppressor gene in which mutations have been linked to disease presentation at a young age. More than 600 distinct pathogenic...

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Kaonga, Patrick
2019·Doctor of Philosophy·University of Zambia

Background: Microbial translocation is a poorly understood consequence of several disorders such as environmental enteropathy (EE) and hepatosplenic schistosomiasis (HSS) disease. Direct biomarkers of microbial translocation such lipopolysaccharide, 16S rRNA gene and Toll-like receptor ligands...

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Kapona, Otridah
2019·Master of Science·University of Zambia

Multidrug-resistant tuberculosis (MDR-TB) is a disease caused by an acid-fast staining pathogenic bacterium, Mycobacterium tuberculosis that is resistant to at least isoniazid (INH) and rifampicin (RIF), the two most potent TB drugs. Drug-resistant tuberculosis poses a significant problem for...

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