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Antimicrobial resistance (AMR) is a global public health and economic threat involving humans, animals and the environment. Globally, AMR threatens historic gains attained in the treatment of infectious diseases. Escherichia coli and Enterococcus species initially considered harmless members of...

HBV infection is a serious infection affecting the liver and causes significant morbidity and mortality in sub-Sahara Africa. While most patients with chronic hepatitis B virus infection are asymptomatic, the infection acquired during infancy or childhood accounts for a disproportionately large...

Febrile seizures (FS) are the most common seizure disorder in childhood. FS and febrile status epilepticus (FSE) are a common presentation at the University Teaching Hospital (UTH) in Lusaka, Zambia. Despite this, the clinical characteristics of children with FS and the associated causes of fever...

Introduction: Diarrhoea is the second commonest cause of under-five mortality globally (second to Pneumonia) and kills one (10 percent) out of every 10 children who die before their fifth birthday. In Zambia dehydration due to diarrhoea is a leading cause of morbidity and mortality among...

In 1952, Virginia Apgar devised a system of scores as a means of evaluating the physical condition of the newborn immediately after birth. The Apgar score has since been accepted for use to assess newborns in almost all labour wards worldwide. While infant mortality is reducing worldwide,...

Background: Congenital Rubella Syndrome (CRS) characterised by heart, eye and hearing defects usually affects an unborn baby when the mother is infected with Rubella virus in the first trimester of pregnancy. It is vaccine preventable and has been eliminated in certain parts of the world. In...

The advent of antiretroviral therapy (ART) has made an impressive impact in the management of HIV infection. However, ART can be responsible for a wide range of toxicities, from low-grade intolerance that may be self-limiting, to life-threatening side-effects. In assessing drug toxicity, mild...

Background: Hepatitis B virus (HBV), Hepatitis C virus (HCV) and HIV are well reported in numerous studies from Europe and America, but there are few data on the prevalence of co-infection in African populations including Zambia. Methods: In this cross-section study, we screened HIV positive...

BACKGROUND – Measles remains the leading cause of vaccine preventable disease that contributes to under 5 mortality rate despite the availability of a safe and effective vaccine. During the 2010-2011 measles outbreak, infants aged 0-8 months constituted 39% of the total population of children...