In healthy persons, blood glucose is maintained in the range 3.5 – 8.0 mmol/L. However, in Diabetes Mellitus (DM) chronic hyperglycemia is observed due to defects in insulin secretion, insulin action or both. This study investigated glucose lowering effects of ethanolic leaf extracts of Cleome...
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A small tree, Steganotaenia araliacae is used as a medicine in local traditional settings in Zambia to initiate and augment parturition although very little is known and documented about its physiological and pharmacological effects. S. araliacae extract (SAEᶜ) has been observed to cause...
Download PDF ↓BACKGROUND: Chronic heart failure patients experience mild, moderate to severe pulmonary dysfunction demonstrated in alterations of FEV1, FVC and FEV1/FVC ratio. About 50% of severe heart failure patients have restrictive lung disease resulting in dyspnea, exercise intolerance and poor quality of...
Background and aim: Carotid femoral pulse wave velocity (cfPWV) is considered as the gold standard for directly estimating central arterial stiffness. Furthermore, the simultaneous measurement of central blood pressure (CBP) with cfPWV is augmentative. This is because the two are strong and...
Introduction: Atrial fibrillation (AF) and congestive heart failure (CHF) have emerged as major global epidemics. These two conditions share common risk factors and frequently coexist. Each condition predisposes to the other, and the concomitant presence of the two has additive adverse effects....
Download PDF ↓Background: Cigarette smoking causes changes in the cardiovascular system including changes resulting from alterations in peripheral resistance such as increase in blood pressure. Increase in Pulse Wave Velocity (PWV), suggesting an increased arterial stiffness has been demonstrated in white...
Download PDF ↓Background: The bark root of Steganotaenia araliacea Hochst (Umbelliferae) nicknamed “herbal pitocin” is used in the traditional circles in Zambia to induce and/or enhance labour. This work was aimed at investigating the contractile stimulatory effects of the aqueous extracts of Steganotaenia...
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