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BACKGROUND:Glucose-6-phosphate dehydrogenase (G6PD) enzyme deficiency is the most common enzymopathy in humans and affects over 400 million people worldwide, majority being in Africa. G6PD catalyses the first reaction of the pentose phosphate pathway where it plays a role in generation of NADPH,...

The barks of the tree known as Loozi Luna Kasiika (LLK) are widely used as a sexual stimulant for treatment of erectile dysfunction. The biochemical pathway responsible for the physiological response was unknown and the goal was to explore the possible signalling pathway that may be involved....