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Background: Appropriate drug utilization has a huge contribution to global reduction in morbidity and mortality. While thousands of patients have been wrongly prescribed statins, others at high risk of cardiovascular accidents (CVA) have been deprived of treatment. According to the Adult...

The incidence of HIV-associated Kaposi’s sarcoma remains high in Zambia in the antiretroviral therapy era. The most efficacious treatment regimen for KS has yet to be established. In both developed and developing countries, treatment regimens have had limited efficacy. Late presentation in Africa...

ABSTRACT Background: Acute poisoning remains a common method employed for suicide worldwide. World Health Organization (WHO) estimates that about 0.3 million people die every year worldwide due to various poisoning agents. Methodology: The study was a cross-sectional descriptive study. A...

Background: Antiretroviral therapy has posed multiple risks and challenges particularly in resource constrained African countries. This is due to the chronic nature of HIV/AIDS disease and hence its therapy, the use of combination therapy and also because therapeutic options and treatment...

Good quality of Technetium 99m eluate (99mTc) as a radionuclide used in diagnostic imaging procedures is important for proper diagnosis, to avoid patients’ unnecessary exposure to radiation and to reduce the number of repeat nuclear imaging. However, presence of impurities in 99mTc eluate, may...

Objectives Drug dosing errors are common in patients with renal impairment and could cause adverse effects and poor outcomes. The study reviewed tenofovir and lamivudine dosing errors as a component of the highly active antiretroviral therapy (HAART) regimen in patients with renal impairment at...

Quality documentation of medication histories at the time of hospital admission with regard to accuracy and completeness is not documented at UTH. A medication history is a detailed, accurate and complete account of all prescribed and non-prescribed medications that a patient had taken or is...

Atazanavir-ritonavir (ATV-r) has been recommended by the World Health Organization as part of second-line combination antiretroviral therapy (cART) in HIV-infected patients aged 6 years and above. In 2013, the Zambia HIV treatment program introduced ATV-ras an alternative Protease Inhibitor (PI)...

Background: Medication errors can occur at any of the five steps of the medication use process: prescribing, transcription, dispensing, administration and monitoring. AIM: This study aimed to ascertain the incidence and types of prescribing and administration errors. METHODS: The study was a...

Background :Sickle cell disease (SCD) is the most common debilitating genetic disorder among people of African descent. The most devastating neurologic manifestation of SCD is stroke. Therapeutic studies of hydroxyurea performed in children include investigations indicating hematologic response,...