Background Environmental enteropathy is prevalent in many low and middle-income countries. Although its aetiology is unknown, we hypothesised that nontuberculous mycobacteria (NTMs), which are ubiquitous in the environment and are known to cause disease in the lungs, the gut, skin, bloodstream...
Download PDF ↓HBV infection is a serious infection affecting the liver and causes significant morbidity and mortality in sub-Sahara Africa. While most patients with chronic hepatitis B virus infection are asymptomatic, the infection acquired during infancy or childhood accounts for a disproportionately large...
Download PDF ↓Background: Cirrhosis is a dominant cause of portal hypertension globally but is overshadowed by schistosomiasis in parts of the tropics, including in Zambia where hepatosplenic schistosomiasis (HSS) sero-prevalence can reach 88% in some districts. Bacterial translocation (BT) drives portal...
Download PDF ↓Background: Oral vaccines have been associated with diminished immunogenicity and efficacy in developing country populations. Rotavirus, cholera and oral polio vaccines have shown much lower protection in Africa and Asia than in developed countries. In view of this, there is an urgent need to...
Download PDF ↓Objective: To determine the various clinical and epidemiological factors associated with peptic ulcer perforation in adults at UTH.A pilot study for an impending broader controlled study. Design: A hospital-based cross-sectional study Participants: 35 adult patients all of whom were diagnosed at...
Download PDF ↓Chronic diarrhea results in salt and water loss resulting in blood volume depletion which may lead to hypovolaemia, postural hypotension and deterioration in quality of life. These may be compounded by metabolic derangements and malnutrition so that these patients suffer from a persistent...
Abdominal tuberculosis is a common form of extra- pulmonary tuberculosis especially in HIV/AIDS patients. A high index of suspicion is required for diagnosis of abdominal tuberculosis in these patients. A study was done at the University Teaching Hospital, Lusaka, Zambia to ascertain whether...
Download PDF ↓Introduction There is a shortage of systematically collected data on gastric cancer in Zambia. An audit carried out as preliminary work showed that there was a change in the epidemiology of gastric cancer since the early 1980s, and it was hypothesised that this change was linked to HIV infection....
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