The John Cunningham virus (JCV) is an opportunistic virus, which leads to the development of progressive multifocal leukoencephalopathy (PML). Infection with the JCV occurs in childhood and the virus remains quiescent in the body, activating during immunosuppression. Exposure to the virus can be...
Download PDF ↓Cardiovascular disease, the major cause of mortality and morbidity in modern societies, is set to overtake infectious diseases in the developing world as the most common cause of death. The increasing prevalence of major and emerging cardiovascular risk factors accounts for this growing burden....
Download PDF ↓Introduction: The spectrum of renal diseases in HIV infected adults undergoing biopsy is vast. Previous studies have indicated that HIV-associated nephropathy (HIVAN) is the commonest diagnosis in HIV-infected patients presenting with renal insufficiency. More than 90% of patients with HIVAN are...
Background: Method: Results: Conclusion Sepsis due to respiratory disease is one of the main complications of HIV/AIDS. Audit data from the Department of Internal Medicine at the University Teaching Hospital in Lusaka, Zambia indicate that pneumonia and tuberculosis in HIV represent two of the...
Background: - Cardiovascular diseases are among the leading cause of morbidity and mortality worldwide. The association between HIV and CVD has been established in many studies. However, information is still lacking on subclinical disease as well as its associated risk factors in this population....
Download PDF ↓Deep vein thrombosis (DVT) and pulmonary embolism (PE) collectively referred to as venous thromboembolism (VTE) are a global concern with substantial morbidity and mortality. Symptomatic DVT commonly occur in hospitalized patients with acute medical illnesses. Thromboprophylaxis for DVT is not...
Download PDF ↓INTRODUCTION: Tuberculosis is recognised as one the leading causes of severe sepsis among HIV positive patients. Most patients with tuberculosis mycobacteraemia have advanced HIV disease with CD4 counts less than 100cells/ul and many do not present with the classical signs of tuberculosis....
Download PDF ↓Background:Amphotericin-B deoxycholate is an essential agent in the management of cryptococcal meningitis. Despite its proven antifungal potency it has several untoward side effects which include renal failure, hypomagnesaemia, hypokalaemia, phlebitis and nephrogenic diabetes insipidus....
Download PDF ↓BACKGROUND Sepsis accounts for a significant burden of morbidity and mortality. In developed countries, it has been implicated as the second leading cause of non-cardiac death. Mortality from sepsis is on the increase with mortality rate of 33-61%. In spite of the high burden of sepsis in...
Download PDF ↓To determine the prevalence of drug adherence and factors associated with poor adherence to antihypertensive treatment Objective:among adults seen in the department of medicine at UTH. To investigate patient related and health care system related factors associated with poor adherence to...
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