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Human Parvovirus (B19V) is a small, single-stranded, non-enveloped DNA virus which is pathogenic to humans causing a wide array of clinical complications which include erythema infectiosum, aplastic crisis and hydrops foetalis. It is generally harmless in healthy individuals but may be life...

Anaemia affects approximately 1.62 billion people globally corresponding to 24.8% of the world’s population. Iron deficiency anaemia (IDA) and anaemia of chronic disease (ACD) are the most common forms of anaemia. A hormone produced by the liver, hepcidin, is the primary regulator of iron...

von Willebrand Disease (vWD) is the most common or prevalent inherited bleeding disorder. It is caused by a deficiency or dysfunction of von Willebrand Factor, which is a glycoprotein that carries Factor VIII (Anti haemophilic factor) and an adhesive protein in platelet-vessel wall interactions....

Spontaneous abortion in Zambia is defined as non-induced embryonic death or passage of products of conception before 28 weeks’ gestation. Placental insufficiency as a result of thrombi lodging in the uteroplacental bed is considered to be a cause of pregnancy loss. Circulating microparticles are...

Vitamin B12 and folate deficiency is a well-known health problem. Deficiencies of folic acid and vitamin B12 are known to cause megaloblastic anaemia, which is characterised by presence of abnormally large erythrocyte precursor cells, megaloblasts, in the bone marrow and macrocytic red cells in...